Genome-Wide Discovery of Drug-Dependent Human Liver Regulatory Elements

Inter-individual variation in gene regulatory elements is hypothesized to play a causative role in adverse drug reactions and reduced drug activity. However, relatively little is known about the location and function of drug-dependent elements. To uncover drug-associated elements in a genome-wide ma...

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Detalles Bibliográficos
Autores principales: Smith, Robin P., Eckalbar, Walter L., Morrissey, Kari M., Luizon, Marcelo R., Hoffmann, Thomas J., Sun, Xuefeng, Jones, Stacy L., Force Aldred, Shelley, Ramamoorthy, Anuradha, Desta, Zeruesenay, Liu, Yunlong, Skaar, Todd C., Trinklein, Nathan D., Giacomini, Kathleen M., Ahituv, Nadav
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4183418/
https://www.ncbi.nlm.nih.gov/pubmed/25275310
http://dx.doi.org/10.1371/journal.pgen.1004648

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