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GIANT: A Cytoscape Plugin for Modular Networks

Network analysis provides deep insight into real complex systems. Revealing the link between topological and functional role of network elements can be crucial to understand the mechanisms underlying the system. Here we propose a Cytoscape plugin (GIANT) to perform network clustering and characteriz...

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Detalles Bibliográficos
Autores principales: Cumbo, Fabio, Paci, Paola, Santoni, Daniele, Di Paola, Luisa, Giuliani, Alessandro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4183485/
https://www.ncbi.nlm.nih.gov/pubmed/25275465
http://dx.doi.org/10.1371/journal.pone.0105001
Descripción
Sumario:Network analysis provides deep insight into real complex systems. Revealing the link between topological and functional role of network elements can be crucial to understand the mechanisms underlying the system. Here we propose a Cytoscape plugin (GIANT) to perform network clustering and characterize nodes at the light of a modified Guimerà-Amaral cartography. This approach results into a vivid picture of the a topological/functional relationship at both local and global level. The plugin has been already approved and uploaded on the Cytoscape APP store.