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Maternal Obesity and Tobacco Use Modify the Impact of Genetic Variants on the Occurrence of Conotruncal Heart Defects

Conotruncal heart defects (CTDs) are among the most severe birth defects worldwide. Studies of CTDs indicate both lifestyle behaviors and genetic variation contribute to the risk of CTDs. Based on a hybrid design using data from 616 case-parental and 1645 control-parental triads recruited for the Na...

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Detalles Bibliográficos
Autores principales: Tang, Xinyu, Nick, Todd G., Cleves, Mario A., Erickson, Stephen W., Li, Ming, Li, Jingyun, MacLeod, Stewart L., Hobbs, Charlotte A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4183535/
https://www.ncbi.nlm.nih.gov/pubmed/25275547
http://dx.doi.org/10.1371/journal.pone.0108903