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Synergy between Sphingosine 1-Phosphate and Lipopolysaccharide Signaling Promotes an Inflammatory, Angiogenic and Osteogenic Response in Human Aortic Valve Interstitial Cells

Given that the bioactive lipid sphingosine 1-phosphate is involved in cardiovascular pathophysiology, and since lipid accumulation and inflammation are hallmarks of calcific aortic stenosis, the role of sphingosine 1-phosphate on the pro-inflammatory/pro-osteogenic pathways in human interstitial cel...

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Detalles Bibliográficos
Autores principales:	Fernández-Pisonero, Isabel, López, Javier, Onecha, Esther, Dueñas, Ana I., Maeso, Patricia, Crespo, Mariano Sánchez, Román, José Alberto San, García-Rodríguez, Carmen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4183546/ https://www.ncbi.nlm.nih.gov/pubmed/25275309 http://dx.doi.org/10.1371/journal.pone.0109081

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