Site-Specific Chemoenzymatic Labeling of Aerolysin Enables the Identification of New Aerolysin Receptors

Aerolysin is a secreted bacterial toxin that perforates the plasma membrane of a target cell with lethal consequences. Previously explored native and epitope-tagged forms of the toxin do not allow site-specific modification of the mature toxin with a probe of choice. We explore sortase-mediated tran...

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Detalles Bibliográficos
Autores principales: Wuethrich, Irene, Peeters, Janneke G. C., Blom, Annet E. M., Theile, Christopher S., Li, Zeyang, Spooner, Eric, Ploegh, Hidde L., Guimaraes, Carla P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4183550/
https://www.ncbi.nlm.nih.gov/pubmed/25275512
http://dx.doi.org/10.1371/journal.pone.0109883

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4183550/
https://www.ncbi.nlm.nih.gov/pubmed/25275512
http://dx.doi.org/10.1371/journal.pone.0109883

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