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Site-Specific Chemoenzymatic Labeling of Aerolysin Enables the Identification of New Aerolysin Receptors
Aerolysin is a secreted bacterial toxin that perforates the plasma membrane of a target cell with lethal consequences. Previously explored native and epitope-tagged forms of the toxin do not allow site-specific modification of the mature toxin with a probe of choice. We explore sortase-mediated tran...
Autores principales: | Wuethrich, Irene, Peeters, Janneke G. C., Blom, Annet E. M., Theile, Christopher S., Li, Zeyang, Spooner, Eric, Ploegh, Hidde L., Guimaraes, Carla P. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4183550/ https://www.ncbi.nlm.nih.gov/pubmed/25275512 http://dx.doi.org/10.1371/journal.pone.0109883 |
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