Cargando…

Cysteine Transport through Excitatory Amino Acid Transporter 3 (EAAT3)

Excitatory amino acid transporters (EAATs) limit glutamatergic signaling and maintain extracellular glutamate concentrations below neurotoxic levels. Of the five known EAAT isoforms (EAATs 1–5), only the neuronal isoform, EAAT3 (EAAC1), can efficiently transport the uncharged amino acid L-cysteine....

Descripción completa

Detalles Bibliográficos
Autores principales: Watts, Spencer D., Torres-Salazar, Delany, Divito, Christopher B., Amara, Susan G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4183567/
https://www.ncbi.nlm.nih.gov/pubmed/25275463
http://dx.doi.org/10.1371/journal.pone.0109245