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Thermosensitive and Mucoadhesive Sol-Gel Composites of Paclitaxel/Dimethyl-β-Cyclodextrin for Buccal Delivery

The purpose of this study was to develop a buccal paclitaxel delivery system using the thermosensitive polymer Pluronic F127 (PF127) and the mucoadhesive polymer polyethylene oxide (PEO). The anticancer agent paclitaxel is usually used to treat ovarian, breast, and non-small-cell lung cancer. To imp...

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Detalles Bibliográficos
Autores principales:	Choi, Soon Gil, Lee, Sang-Eun, Kang, Bong-Seok, Ng, Choon Lian, Davaa, Enkhzaya, Park, Jeong-Sook
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4183572/ https://www.ncbi.nlm.nih.gov/pubmed/25275485 http://dx.doi.org/10.1371/journal.pone.0109090

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