Exosomes from Hepatitis C Infected Patients Transmit HCV Infection and Contain Replication Competent Viral RNA in Complex with Ago2-miR122-HSP90

Antibodies targeting receptor-mediated entry of HCV into hepatocytes confer limited therapeutic benefits. Evidence suggests that exosomes can transfer genetic materials between cells; however, their role in HCV infection remains obscure. Here, we show that exosomes isolated from sera of chronic HCV...

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Detalles Bibliográficos
Autores principales: Bukong, Terence N., Momen-Heravi, Fatemeh, Kodys, Karen, Bala, Shashi, Szabo, Gyongyi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4183590/
https://www.ncbi.nlm.nih.gov/pubmed/25275643
http://dx.doi.org/10.1371/journal.ppat.1004424

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4183590/
https://www.ncbi.nlm.nih.gov/pubmed/25275643
http://dx.doi.org/10.1371/journal.ppat.1004424

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