Single-Molecule Patch-Clamp FRET Microscopy Studies of NMDA Receptor Ion Channel Dynamics in Living Cells: Revealing the Multiple Conformational States Associated with a Channel at Its Electrical Off State

[Image: see text] Conformational dynamics plays a critical role in the activation, deactivation, and open–close activities of ion channels in living cells. Such conformational dynamics is often inhomogeneous and extremely difficult to be directly characterized by ensemble-averaged spectroscopic imag...

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Detalles Bibliográficos
Autores principales: Sasmal, Dibyendu Kumar, Lu, H. Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4183623/
https://www.ncbi.nlm.nih.gov/pubmed/25148304
http://dx.doi.org/10.1021/ja506231j

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4183623/
https://www.ncbi.nlm.nih.gov/pubmed/25148304
http://dx.doi.org/10.1021/ja506231j

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