Cargando…

A Fibril-Like Assembly of Oligomers of a Peptide Derived from β-Amyloid

[Image: see text] A macrocyclic β-sheet peptide containing two nonapeptide segments based on Aβ(15–23) (QKLVFFAED) forms fibril-like assemblies of oligomers in the solid state. The X-ray crystallographic structure of macrocyclic β-sheet peptide 3 was determined at 1.75 Å resolution. The macrocycle f...

Descripción completa

Detalles Bibliográficos
Autores principales: Pham, Johnny D., Spencer, Ryan K., Chen, Kevin H., Nowick, James S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4183627/
https://www.ncbi.nlm.nih.gov/pubmed/25068693
http://dx.doi.org/10.1021/ja505713y