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Both Transmembrane Domains of BK β1 Subunits Are Essential to Confer the Normal Phenotype of β1-Containing BK Channels
Voltage/Ca(2+) (i)-gated, large conductance K(+) (BK) channels result from tetrameric association of α (slo1) subunits. In most tissues, BK protein complexes include regulatory β subunits that contain two transmembrane domains (TM1, TM2), an extracellular loop, and two short intracellular termini. F...
Autores principales: | Kuntamallappanavar, Guruprasad, Toro, Ligia, Dopico, Alex M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4183656/ https://www.ncbi.nlm.nih.gov/pubmed/25275635 http://dx.doi.org/10.1371/journal.pone.0109306 |
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