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Single luminal epithelial progenitors can generate prostate organoids in culture
The intrinsic ability to display self-organizing morphogenetic properties in ex vivo culture may represent a general property of tissue stem cells. Here we show that single luminal stem/progenitor cells can generate prostate organoids in a three-dimensional culture system in the absence of stroma. O...
Autores principales: | Chua, Chee Wai, Shibata, Maho, Lei, Ming, Toivanen, Roxanne, Barlow, LaMont J., Bergren, Sarah K., Badani, Ketan K., McKiernan, James M., Benson, Mitchell C., Hibshoosh, Hanina, Shen, Michael M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4183706/ https://www.ncbi.nlm.nih.gov/pubmed/25241035 http://dx.doi.org/10.1038/ncb3047 |
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