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Single luminal epithelial progenitors can generate prostate organoids in culture

The intrinsic ability to display self-organizing morphogenetic properties in ex vivo culture may represent a general property of tissue stem cells. Here we show that single luminal stem/progenitor cells can generate prostate organoids in a three-dimensional culture system in the absence of stroma. O...

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Detalles Bibliográficos
Autores principales: Chua, Chee Wai, Shibata, Maho, Lei, Ming, Toivanen, Roxanne, Barlow, LaMont J., Bergren, Sarah K., Badani, Ketan K., McKiernan, James M., Benson, Mitchell C., Hibshoosh, Hanina, Shen, Michael M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4183706/
https://www.ncbi.nlm.nih.gov/pubmed/25241035
http://dx.doi.org/10.1038/ncb3047

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