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BRCA1 mRNA levels following a 4–6-week intervention with oral 3,3′-diindolylmethane
BACKGROUND: Haploinsufficiency may contribute to the development of breast cancer among women with a BRCA1 mutation. Thus, interventions that enhance BRCA1 expression may represent avenues for prevention. Studies have shown that 3,3′-diindolylmethane (DIM) can upregulate BRCA1 expression in breast c...
Autores principales: | Kotsopoulos, J, Zhang, S, Akbari, M, Salmena, L, Llacuachaqui, M, Zeligs, M, Sun, P, Narod, S A |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4183839/ https://www.ncbi.nlm.nih.gov/pubmed/25025957 http://dx.doi.org/10.1038/bjc.2014.391 |
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