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The lag time in initiating clinical testing of new drugs in combination with radiation therapy, a significant barrier to progress?
BACKGROUND: The clinical development of new drugs with radiation appears to be limited. We hypothesised that phase I clinical trials with radiation therapy (RT) are initiated too late into a new drug's lifetime, impeding the ability to complete RT–drug development programmes before patent expir...
Autores principales: | Blumenfeld, P, Pfeffer, R M, Symon, Z, Den, R B, Dicker, A P, Raben, D, Lawrence, Y R |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4183859/ https://www.ncbi.nlm.nih.gov/pubmed/25117813 http://dx.doi.org/10.1038/bjc.2014.448 |
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