Genetic Instability of Influenza pH1N1 Viruses

Here, we report full-length genome sequences of influenza pH1N1 viruses obtained prior to and after propagation in MDCK cells. Paired comparisons of the genomes showed that each strain acquired 1.0 to 18.8 mutations per genome per replication cycle, which corresponds to 0.5 to 5.8 mutations per viru...

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Detalles Bibliográficos
Autores principales: Jalovaara, Petri, Bychkov, Dmitrii, Ahtiainen, Laura, Kallio-Kokko, Hannimari, Valkonen, Miia, Kantele, Anu, Mattila, Pirkko, Almusa, Henrikki, Kallioniemi, Olli, Kainov, Denis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2014
Materias:
Viruses
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4183864/
https://www.ncbi.nlm.nih.gov/pubmed/25278520
http://dx.doi.org/10.1128/genomeA.00841-14

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