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Preclinical and Clinical Investigations of Mood Stabilizers for Huntington's Disease: What Have We Learned?
Huntington's disease (HD) is a lethal, autosomal dominant neurodegenerative disorder caused by CAG repeat expansions at exon 1 of the huntingtin (Htt) gene, which encodes for a mutant huntingtin protein (mHtt). Prominent symptoms of HD include motor dysfunction, characterized by chorea; psychia...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Ivyspring International Publisher
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4183923/ https://www.ncbi.nlm.nih.gov/pubmed/25285035 http://dx.doi.org/10.7150/ijbs.9898 |