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A New Entry to Azomethine Ylides from Allylic Amines and Glyoxals: Shifting the Reliance on Amino Ester Precursors

[Image: see text] The first examples of azomethine ylides derived from allylic amine and glyoxal precursors are reported. The condensation of primary allylic and α-aryl amines with glyoxylates or α-aryl glyoxals affords conjugated azomethine ylides that undergo facile [3 + 2] cycloaddition, providin...

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Detalles Bibliográficos
Autores principales: Machamer, Natalie K., Liu, Xiaoxi, Waters, Stephen P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4184444/
https://www.ncbi.nlm.nih.gov/pubmed/25247255
http://dx.doi.org/10.1021/ol5022614