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Presentation of pulmonary Langerhans cell histiocytosis before the development of lung cysts

Pulmonary Langerhans cell histiocytosis (PLCH) affects mainly young, predominantly smoking adults with a peak at 20–40 years of age. Patients with PLCH often present with a nonproductive cough and/or dyspnea. High-resolution CT (HRCT) is the most important diagnostic modality in PLCH. The typical HR...

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Detalles Bibliográficos
Autores principales: Martin, Irene, Ballester, Marta, Ruiz, Yolanda, Llatjós, Roger, Alarza, Fernando, Molina, Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4184522/
https://www.ncbi.nlm.nih.gov/pubmed/25473537
http://dx.doi.org/10.1002/rcr2.11
Descripción
Sumario:Pulmonary Langerhans cell histiocytosis (PLCH) affects mainly young, predominantly smoking adults with a peak at 20–40 years of age. Patients with PLCH often present with a nonproductive cough and/or dyspnea. High-resolution CT (HRCT) is the most important diagnostic modality in PLCH. The typical HRCT pattern combines small poorly limited nodules, cavitated nodules, and finally thick- and thin-walled cysts. In rare cases, HRCT enables PLCH to be diagnosed prior to the development of cysts.