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Hyperacute ischemic stroke without lesions on diffusion-weighted imaging in a patient treated with rtPA thrombolysis

KEY CLINICAL MESSAGE: We report a comatose patient with severe neurological deficits who was without spontaneous language or movement. He had a good response to recombinant tissue plasminogen activator (rtPA) thrombolysis even though there were no detectable lesions on diffusion-weighted imaging (DW...

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Detalles Bibliográficos
Autores principales: Jing, Zhen, Zhang, Shijun, Tang, Jingjing, Xu, Anding, Ruan, Yiwen, Huang, Li'an
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4184595/
https://www.ncbi.nlm.nih.gov/pubmed/25356251
http://dx.doi.org/10.1002/ccr3.60
Descripción
Sumario:KEY CLINICAL MESSAGE: We report a comatose patient with severe neurological deficits who was without spontaneous language or movement. He had a good response to recombinant tissue plasminogen activator (rtPA) thrombolysis even though there were no detectable lesions on diffusion-weighted imaging (DWI). DWI is very sensitive for diagnosing hyperacute ischemic stroke, and rtPA thrombolysis is the best treatment. However, rtPA thrombolysis in ischemic stroke patients without lesions on DWI has rarely been reported.