Hyperacute ischemic stroke without lesions on diffusion-weighted imaging in a patient treated with rtPA thrombolysis

KEY CLINICAL MESSAGE: We report a comatose patient with severe neurological deficits who was without spontaneous language or movement. He had a good response to recombinant tissue plasminogen activator (rtPA) thrombolysis even though there were no detectable lesions on diffusion-weighted imaging (DW...

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Autores principales: Jing, Zhen, Zhang, Shijun, Tang, Jingjing, Xu, Anding, Ruan, Yiwen, Huang, Li'an
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2014
Materias:
Case Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4184595/
https://www.ncbi.nlm.nih.gov/pubmed/25356251
http://dx.doi.org/10.1002/ccr3.60
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author Jing, Zhen
Zhang, Shijun
Tang, Jingjing
Xu, Anding
Ruan, Yiwen
Huang, Li'an
author_facet Jing, Zhen
Zhang, Shijun
Tang, Jingjing
Xu, Anding
Ruan, Yiwen
Huang, Li'an
author_sort Jing, Zhen
collection PubMed
description KEY CLINICAL MESSAGE: We report a comatose patient with severe neurological deficits who was without spontaneous language or movement. He had a good response to recombinant tissue plasminogen activator (rtPA) thrombolysis even though there were no detectable lesions on diffusion-weighted imaging (DWI). DWI is very sensitive for diagnosing hyperacute ischemic stroke, and rtPA thrombolysis is the best treatment. However, rtPA thrombolysis in ischemic stroke patients without lesions on DWI has rarely been reported.
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spelling pubmed-41845952014-10-29 Hyperacute ischemic stroke without lesions on diffusion-weighted imaging in a patient treated with rtPA thrombolysis Jing, Zhen Zhang, Shijun Tang, Jingjing Xu, Anding Ruan, Yiwen Huang, Li'an Clin Case Rep Case Reports KEY CLINICAL MESSAGE: We report a comatose patient with severe neurological deficits who was without spontaneous language or movement. He had a good response to recombinant tissue plasminogen activator (rtPA) thrombolysis even though there were no detectable lesions on diffusion-weighted imaging (DWI). DWI is very sensitive for diagnosing hyperacute ischemic stroke, and rtPA thrombolysis is the best treatment. However, rtPA thrombolysis in ischemic stroke patients without lesions on DWI has rarely been reported. Blackwell Publishing Ltd 2014-06 2014-03-16 /pmc/articles/PMC4184595/ /pubmed/25356251 http://dx.doi.org/10.1002/ccr3.60 Text en © 2014 The Authors. Clinical Case Reports published by John Wiley & Sons Ltd. http://creativecommons.org/licenses/by-nc-nd/3.0/ This is an open access article under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.
spellingShingle Case Reports
Jing, Zhen
Zhang, Shijun
Tang, Jingjing
Xu, Anding
Ruan, Yiwen
Huang, Li'an
Hyperacute ischemic stroke without lesions on diffusion-weighted imaging in a patient treated with rtPA thrombolysis
title Hyperacute ischemic stroke without lesions on diffusion-weighted imaging in a patient treated with rtPA thrombolysis
title_full Hyperacute ischemic stroke without lesions on diffusion-weighted imaging in a patient treated with rtPA thrombolysis
title_fullStr Hyperacute ischemic stroke without lesions on diffusion-weighted imaging in a patient treated with rtPA thrombolysis
title_full_unstemmed Hyperacute ischemic stroke without lesions on diffusion-weighted imaging in a patient treated with rtPA thrombolysis
title_short Hyperacute ischemic stroke without lesions on diffusion-weighted imaging in a patient treated with rtPA thrombolysis
title_sort hyperacute ischemic stroke without lesions on diffusion-weighted imaging in a patient treated with rtpa thrombolysis
topic Case Reports
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4184595/
https://www.ncbi.nlm.nih.gov/pubmed/25356251
http://dx.doi.org/10.1002/ccr3.60
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