Chronic myelomonocytic leukemia presenting with polyserositis due to an immune-mediated monocyte activation

KEY CLINICAL MESSAGE: Monocytosis is often profoundly implicated in chronic myelomonocytic leukemia (CMML). We diagnosed a 63-year-old woman with CMML involving heterochronological systemic polyserositis with infiltrating benign monocytes. The patient's pleural effusion was eliminated completel...

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Detalles Bibliográficos
Autores principales: Imataki, Osamu, Watanabe, Naoki, Matsumoto, Kensuke, Uemura, Makiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2014
Materias:
Case Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4184627/
https://www.ncbi.nlm.nih.gov/pubmed/25356241
http://dx.doi.org/10.1002/ccr3.55
Descripción
Sumario:KEY CLINICAL MESSAGE: Monocytosis is often profoundly implicated in chronic myelomonocytic leukemia (CMML). We diagnosed a 63-year-old woman with CMML involving heterochronological systemic polyserositis with infiltrating benign monocytes. The patient's pleural effusion was eliminated completely with corticosteroid therapy. We speculate that our case represents an immunological reaction with activated monocytes triggered by infection.

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