First report of the ceftazidimase CTX-M-19 in South America

We report the first detection of bla(CTX-M-19) in South America, harboured in an Escherichia coli isolate obtained from a urine sample; such an isolate belonged to phylogenetic group A, ST603, and showed a ceftazidimase profile. bla(CTX-M-19) was encoded in an approximately 100 kb IncI1/IncF conjuga...

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Detalles Bibliográficos
Autores principales: García-Fulgueiras, V, Bado, I, Cordeiro, N F, Algorta, G, Vignoli, R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2013
Materias:
New Microbes in Humans – New Resistant Microbes in Humans
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4184694/
https://www.ncbi.nlm.nih.gov/pubmed/25356329
http://dx.doi.org/10.1002/nmi2.25
Descripción
Sumario:We report the first detection of bla(CTX-M-19) in South America, harboured in an Escherichia coli isolate obtained from a urine sample; such an isolate belonged to phylogenetic group A, ST603, and showed a ceftazidimase profile. bla(CTX-M-19) was encoded in an approximately 100 kb IncI1/IncF conjugative plasmid, featuring pndAC and hok/sok addiction systems; the β-lactamase gene was flanked upstream by three tandem-like transposons (IS26, IS10 and ISEcp1), inserted one inside the other, and downstream by IS903.

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