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PDGF-D Expression Is Down-Regulated by TGFβ in Fibroblasts
Transforming growth factor-β (TGFβ) is a key mediator of fibrogenesis. TGFβ is overexpressed and activated in fibrotic diseases, regulates fibroblast differentiation into myofibroblasts and induces extracellular matrix deposition. Platelet-derived growth factor (PDGF) is also a regulator of fibrogen...
Autores principales: | Charni Chaabane, Saima, Coomans de Brachène, Alexandra, Essaghir, Ahmed, Velghe, Amélie, Lo Re, Sandra, Stockis, Julie, Lucas, Sophie, Khachigian, Levon M., Huaux, François, Demoulin, Jean-Baptiste |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4184810/ https://www.ncbi.nlm.nih.gov/pubmed/25280005 http://dx.doi.org/10.1371/journal.pone.0108656 |
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