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Clathrin Assembly Protein CALM Plays a Critical Role in KIT Signaling by Regulating Its Cellular Transport from Early to Late Endosomes in Hematopoietic Cells
CALM is implicated in the formation of clathrin-coated vesicles, which mediate endocytosis and intracellular trafficking of growth factor receptors and nutrients. We previously found that CALM-deficient mice suffer from severe anemia due to the impaired clathrin-mediated endocytosis of transferrin r...
Autores principales: | Rai, Shinya, Tanaka, Hirokazu, Suzuki, Mai, Ogoh, Honami, Taniguchi, Yasuhiro, Morita, Yasuyoshi, Shimada, Takahiro, Tanimura, Akira, Matsui, Keiko, Yokota, Takafumi, Oritani, Kenji, Tanabe, Kenji, Watanabe, Toshio, Kanakura, Yuzuru, Matsumura, Itaru |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4184852/ https://www.ncbi.nlm.nih.gov/pubmed/25279552 http://dx.doi.org/10.1371/journal.pone.0109441 |
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