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In Vivo Time-Related Evaluation of a Therapeutic Neutralization Monoclonal Antibody against Lethal Enterovirus 71 Infection in a Mouse Model

Enterovirus 71 (EV71) is a neurotropic virus capable of inducing severe neurological symptoms and death. No direct targeting antivirals are useful in the treatment of severe EV71 infection. Because of low toxicity and good specificity, monoclonal antibodies (MAb) are a potential candidate for the tr...

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Detalles Bibliográficos
Autores principales: Li, Zhiqun, Xu, Longfa, He, Delei, Yang, Lisheng, Liu, Che, Chen, Yixin, Shih, James Wai Kuo, Zhang, Jun, Zhao, Qinjian, Cheng, Tong, Xia, Ningshao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4184856/
https://www.ncbi.nlm.nih.gov/pubmed/25279734
http://dx.doi.org/10.1371/journal.pone.0109391