Histone Deacetylase 1/Sp1/MicroRNA-200b Signaling Accounts for Maintenance of Cancer Stem-Like Cells in Human Lung Adenocarcinoma

The presence of cancer stem-like cells (CSCs) is one of the mechanisms responsible for chemoresistance that has been a major hindrance towards lung adenocarcinoma (LAD) treatment. Recently, we have identified microRNA (miR)-200b as a key regulator of chemoresistance in human docetaxel-resistant LAD...

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Detalles Bibliográficos
Autores principales: Chen, Dong-Qin, Huang, Jia-Yuan, Feng, Bing, Pan, Ban-Zhou, De, Wei, Wang, Rui, Chen, Long-Bang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4184862/
https://www.ncbi.nlm.nih.gov/pubmed/25279705
http://dx.doi.org/10.1371/journal.pone.0109578

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