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PSMA-Specific CAR-Engineered T Cells Eradicate Disseminated Prostate Cancer in Preclinical Models
Immunology-based interventions have been proposed as a promising curative chance to effectively attack postoperative minimal residual disease and distant metastatic localizations of prostate tumors. We developed a chimeric antigen receptor (CAR) construct targeting the human prostate-specific membra...
Autores principales: | Zuccolotto, Gaia, Fracasso, Giulio, Merlo, Anna, Montagner, Isabella Monia, Rondina, Maria, Bobisse, Sara, Figini, Mariangela, Cingarlini, Sara, Colombatti, Marco, Zanovello, Paola, Rosato, Antonio |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4184866/ https://www.ncbi.nlm.nih.gov/pubmed/25279468 http://dx.doi.org/10.1371/journal.pone.0109427 |
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