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A long non-coding RNA protects the heart from pathological hypertrophy

The role of long noncoding RNA (lncRNA) in adult hearts is unknown; also unclear is how lncRNA modulates nucleosome remodeling. An estimated 70% of mouse genes undergo antisense transcription(1), including myosin heavy chain 7 (Myh7) that encodes molecular motor proteins for heart contraction(2). He...

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Detalles Bibliográficos
Autores principales: Han, Pei, Li, Wei, Lin, Chiou-Hong, Yang, Jin, Shang, Ching, Nuernberg, Sylvia T., Jin, Kevin Kai, Xu, Weihong, Lin, Chieh-Yu, Lin, Chien-Jung, Xiong, Yiqin, Chien, Huanchieh, Zhou, Bin, Ashley, Euan, Bernstein, Daniel, Chen, Peng-Sheng, Chen, Huei-sheng Vincent, Quertermous, Thomas, Chang, Ching-Pin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4184960/
https://www.ncbi.nlm.nih.gov/pubmed/25119045
http://dx.doi.org/10.1038/nature13596