Drug-induced visceral angioedema

Angioedema associated with angiotensin converting enzyme inhibitors (ACEIs) is due to the accumulation of bradykinin and its metabolites. Angiotensin receptor blockers (ARBs) produce anti-hypertensive effects by blocking the angiotensin II AT1 receptor action; hence bradykinin-related side effects a...

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Autores principales: Thalanayar, Prashanth M., Ghobrial, Ibrahim, Lubin, Fritz, Karnik, Reena, Bhasin, Robin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Co-Action Publishing 2014
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4185149/
https://www.ncbi.nlm.nih.gov/pubmed/25317271
http://dx.doi.org/10.3402/jchimp.v4.25260
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author Thalanayar, Prashanth M.
Ghobrial, Ibrahim
Lubin, Fritz
Karnik, Reena
Bhasin, Robin
author_facet Thalanayar, Prashanth M.
Ghobrial, Ibrahim
Lubin, Fritz
Karnik, Reena
Bhasin, Robin
author_sort Thalanayar, Prashanth M.
collection PubMed
description Angioedema associated with angiotensin converting enzyme inhibitors (ACEIs) is due to the accumulation of bradykinin and its metabolites. Angiotensin receptor blockers (ARBs) produce anti-hypertensive effects by blocking the angiotensin II AT1 receptor action; hence bradykinin-related side effects are not expected. However, we notice the occurrence of ARB-induced angioedema as not a very rare side effect. Visceral drug-induced angioedema has been reported with ACEIs, not with ARBs. This underlying review will help educate readers on the pathophysiology and recent guidelines pertaining to ACEI- and ARB-induced visceral angioedema.
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spelling pubmed-41851492014-10-14 Drug-induced visceral angioedema Thalanayar, Prashanth M. Ghobrial, Ibrahim Lubin, Fritz Karnik, Reena Bhasin, Robin J Community Hosp Intern Med Perspect Review Article Angioedema associated with angiotensin converting enzyme inhibitors (ACEIs) is due to the accumulation of bradykinin and its metabolites. Angiotensin receptor blockers (ARBs) produce anti-hypertensive effects by blocking the angiotensin II AT1 receptor action; hence bradykinin-related side effects are not expected. However, we notice the occurrence of ARB-induced angioedema as not a very rare side effect. Visceral drug-induced angioedema has been reported with ACEIs, not with ARBs. This underlying review will help educate readers on the pathophysiology and recent guidelines pertaining to ACEI- and ARB-induced visceral angioedema. Co-Action Publishing 2014-09-29 /pmc/articles/PMC4185149/ /pubmed/25317271 http://dx.doi.org/10.3402/jchimp.v4.25260 Text en © 2014 Prashanth M. Thalanayar et al. http://creativecommons.org/licenses/by-nc-nd/3.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution-Noncommercial 3.0 Unported License, permitting all non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review Article
Thalanayar, Prashanth M.
Ghobrial, Ibrahim
Lubin, Fritz
Karnik, Reena
Bhasin, Robin
Drug-induced visceral angioedema
title Drug-induced visceral angioedema
title_full Drug-induced visceral angioedema
title_fullStr Drug-induced visceral angioedema
title_full_unstemmed Drug-induced visceral angioedema
title_short Drug-induced visceral angioedema
title_sort drug-induced visceral angioedema
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4185149/
https://www.ncbi.nlm.nih.gov/pubmed/25317271
http://dx.doi.org/10.3402/jchimp.v4.25260
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