Tumor-secreted miR-214 induces regulatory T cells: a major link between immune evasion and tumor growth

An increased population of CD4(+)CD25(high)Foxp3(+) regulatory T cells (Tregs) in the tumor-associated microenvironment plays an important role in cancer immune evasion. However, the underlying mechanism remains unclear. Here we observed an increased secretion of miR-214 in various types of human ca...

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Detalles Bibliográficos
Autores principales: Yin, Yuan, Cai, Xing, Chen, Xi, Liang, Hongwei, Zhang, Yujing, Li, Jing, Wang, Zuoyun, Chen, Xiulan, Zhang, Wen, Yokoyama, Seiji, Wang, Cheng, Li, Liang, Li, Limin, Hou, Dongxia, Dong, Lei, Xu, Tao, Hiroi, Takachika, Yang, Fuquan, Ji, Hongbin, Zhang, Junfeng, Zen, Ke, Zhang, Chen-Yu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4185347/
https://www.ncbi.nlm.nih.gov/pubmed/25223704
http://dx.doi.org/10.1038/cr.2014.121

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