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An endocytosis pathway initiated through neuropilin-1 and regulated by nutrient availability
Neuropilins (NRPs) are trans-membrane receptors involved in axon guidance and vascular development. Many growth factors and other signaling molecules bind to NRPs through a C-terminal, basic sequence motif (C-end Rule or CendR motif). Peptides with this motif (CendR peptides) are taken up into cells...
Autores principales: | Pang, Hong-Bo, Braun, Gary B., Friman, Tomas, Aza-Blanc, Pedro, Ruidiaz, Manuel E., Sugahara, Kazuki N., Teesalu, Tambet, Ruoslahti, Erkki |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4185402/ https://www.ncbi.nlm.nih.gov/pubmed/25277522 http://dx.doi.org/10.1038/ncomms5904 |
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