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An endocytosis pathway initiated through neuropilin-1 and regulated by nutrient availability

Neuropilins (NRPs) are trans-membrane receptors involved in axon guidance and vascular development. Many growth factors and other signaling molecules bind to NRPs through a C-terminal, basic sequence motif (C-end Rule or CendR motif). Peptides with this motif (CendR peptides) are taken up into cells...

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Detalles Bibliográficos
Autores principales: Pang, Hong-Bo, Braun, Gary B., Friman, Tomas, Aza-Blanc, Pedro, Ruidiaz, Manuel E., Sugahara, Kazuki N., Teesalu, Tambet, Ruoslahti, Erkki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4185402/
https://www.ncbi.nlm.nih.gov/pubmed/25277522
http://dx.doi.org/10.1038/ncomms5904

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