Cargando…
Are cases of mumps in vaccinated patients attributable to mismatches in both vaccine T-cell and B-cell epitopes?: An immunoinformatic analysis
Resurgent mumps outbreaks have raised questions about the current efficacy of mumps vaccines. We have applied immunoinformatics techniques based on principal component analysis to evaluate patterns in predicted B-cell linear epitopes, MHC binding affinity and cathepsin cleavage in the hemagglutinin...
Autores principales: | Homan, E Jane, Bremel, Robert D |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Landes Bioscience
2014
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4185895/ https://www.ncbi.nlm.nih.gov/pubmed/24275080 http://dx.doi.org/10.4161/hv.27139 |
Ejemplares similares
-
T-cell epitope vaccine design by immunoinformatics
por: Patronov, Atanas, et al.
Publicado: (2013) -
Patterns of Predicted T-Cell Epitopes Associated with Antigenic Drift in Influenza H3N2 Hemagglutinin
por: Homan, E. Jane, et al.
Publicado: (2011) -
A Role for Epitope Networking in Immunomodulation by Helminths
por: Homan, E. Jane, et al.
Publicado: (2018) -
Extensive T-Cell Epitope Repertoire Sharing among Human Proteome, Gastrointestinal Microbiome, and Pathogenic Bacteria: Implications for the Definition of Self
por: Bremel, Robert D., et al.
Publicado: (2015) -
Immunoinformatic Analysis of T- and B-Cell Epitopes for SARS-CoV-2 Vaccine Design
por: Wang, Dongliang, et al.
Publicado: (2020)