Cargando…
Crystal structure of 1,3-dimethyl-3-phenylpyrrolidine-2,5-dione: a clinically used anticonvulsant
In the title compound, C(12)H(13)NO(2), the five-membered ring has an envelope conformation; the disubstituted C atom lies out of the mean plane through the four other ring atoms (r.m.s. deviation = 0.0038 Å) by 0.1877 (18) Å. The plane of the phenyl substituent is practically perpendicular to that...
Autores principales: | , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
International Union of Crystallography
2014
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4186160/ https://www.ncbi.nlm.nih.gov/pubmed/25309268 http://dx.doi.org/10.1107/S1600536814016717 |
Sumario: | In the title compound, C(12)H(13)NO(2), the five-membered ring has an envelope conformation; the disubstituted C atom lies out of the mean plane through the four other ring atoms (r.m.s. deviation = 0.0038 Å) by 0.1877 (18) Å. The plane of the phenyl substituent is practically perpendicular to that of the planar part of the five-membered ring, with a dihedral angle of 87.01 (5)°. In the crystal, molecules are linked by weak C—H⋯O hydrogen bonds, forming inversion dimers. The dimers are linked by further C—H⋯O hydrogen bonds, as well as carbonyl–carbonyl attractive interactions [O⋯C = 3.2879 (19) Å], forming a three-dimensional framework structure. |
---|