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Crystal structure of 1,3-dimethyl-3-phenyl­pyrrolidine-2,5-dione: a clinically used anti­convulsant

In the title compound, C(12)H(13)NO(2), the five-membered ring has an envelope conformation; the disubstituted C atom lies out of the mean plane through the four other ring atoms (r.m.s. deviation = 0.0038 Å) by 0.1877 (18) Å. The plane of the phenyl substituent is practically perpendicular to that...

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Detalles Bibliográficos
Autores principales: Ordonez, Carlos, Pavlovetc, Ilia M., Khrustalev, Victor N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4186160/
https://www.ncbi.nlm.nih.gov/pubmed/25309268
http://dx.doi.org/10.1107/S1600536814016717
Descripción
Sumario:In the title compound, C(12)H(13)NO(2), the five-membered ring has an envelope conformation; the disubstituted C atom lies out of the mean plane through the four other ring atoms (r.m.s. deviation = 0.0038 Å) by 0.1877 (18) Å. The plane of the phenyl substituent is practically perpendicular to that of the planar part of the five-membered ring, with a dihedral angle of 87.01 (5)°. In the crystal, mol­ecules are linked by weak C—H⋯O hydrogen bonds, forming inversion dimers. The dimers are linked by further C—H⋯O hydrogen bonds, as well as carbon­yl–carbonyl attractive inter­actions [O⋯C = 3.2879 (19) Å], forming a three-dimensional framework structure.