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Crystal structure of 1-cyclopropanecarbonyl-3-methyl-2,6-di-p-tolylpiperidin-4-one
The title compound, C(24)H(27)NO(2), crystallizes with two independent molecules (A and B) in the asymmetric unit. The two molecules have very similar conformations and each exhibits an intramolecular C—H⋯π interaction. The central piperidine rings adopt boat conformations and the p-tolyl rings...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
International Union of Crystallography
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4186191/ https://www.ncbi.nlm.nih.gov/pubmed/25309223 http://dx.doi.org/10.1107/S1600536814018546 |
Sumario: | The title compound, C(24)H(27)NO(2), crystallizes with two independent molecules (A and B) in the asymmetric unit. The two molecules have very similar conformations and each exhibits an intramolecular C—H⋯π interaction. The central piperidine rings adopt boat conformations and the p-tolyl rings are inclined to the mean plane of the piperidine ring by 71.21 (11) and 89.86 (12)° in molecule A and by 68.01 (12) and 89.33 (12)° in molecule B. The cyclopropanecarbonyl group is oriented at an angle of 68.5 (2)° with respect to the mean plane of the piperidine ring in molecule A and 66.2 (2)° in molecule B. In the crystal, the A and B molecules are linked by C—H⋯O hydrogen bonds, enclosing R (2) (1)(6) ring motifs, forming ribbons running along the a-axis direction. |
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