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Crystal structure of 1-cyclo­propane­carbon­yl-3-methyl-2,6-di-p-tolyl­piperidin-4-one

The title compound, C(24)H(27)NO(2), crystallizes with two independent mol­ecules (A and B) in the asymmetric unit. The two mol­ecules have very similar conformations and each exhibits an intra­molecular C—H⋯π inter­action. The central piperidine rings adopt boat conformations and the p-tolyl rings...

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Autores principales: Kamaraj, A., Ranjith, S., Rajkumar, R., Mohanraj, G., Krishnasamy, K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4186191/
https://www.ncbi.nlm.nih.gov/pubmed/25309223
http://dx.doi.org/10.1107/S1600536814018546
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author Kamaraj, A.
Ranjith, S.
Rajkumar, R.
Mohanraj, G.
Krishnasamy, K.
author_facet Kamaraj, A.
Ranjith, S.
Rajkumar, R.
Mohanraj, G.
Krishnasamy, K.
author_sort Kamaraj, A.
collection PubMed
description The title compound, C(24)H(27)NO(2), crystallizes with two independent mol­ecules (A and B) in the asymmetric unit. The two mol­ecules have very similar conformations and each exhibits an intra­molecular C—H⋯π inter­action. The central piperidine rings adopt boat conformations and the p-tolyl rings are inclined to the mean plane of the piperidine ring by 71.21 (11) and 89.86 (12)° in mol­ecule A and by 68.01 (12) and 89.33 (12)° in mol­ecule B. The cyclopropanecarbonyl group is oriented at an angle of 68.5 (2)° with respect to the mean plane of the piperidine ring in mol­ecule A and 66.2 (2)° in mol­ecule B. In the crystal, the A and B mol­ecules are linked by C—H⋯O hydrogen bonds, enclosing R (2) (1)(6) ring motifs, forming ribbons running along the a-axis direction.
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spelling pubmed-41861912014-10-12 Crystal structure of 1-cyclo­propane­carbon­yl-3-methyl-2,6-di-p-tolyl­piperidin-4-one Kamaraj, A. Ranjith, S. Rajkumar, R. Mohanraj, G. Krishnasamy, K. Acta Crystallogr Sect E Struct Rep Online Data Reports The title compound, C(24)H(27)NO(2), crystallizes with two independent mol­ecules (A and B) in the asymmetric unit. The two mol­ecules have very similar conformations and each exhibits an intra­molecular C—H⋯π inter­action. The central piperidine rings adopt boat conformations and the p-tolyl rings are inclined to the mean plane of the piperidine ring by 71.21 (11) and 89.86 (12)° in mol­ecule A and by 68.01 (12) and 89.33 (12)° in mol­ecule B. The cyclopropanecarbonyl group is oriented at an angle of 68.5 (2)° with respect to the mean plane of the piperidine ring in mol­ecule A and 66.2 (2)° in mol­ecule B. In the crystal, the A and B mol­ecules are linked by C—H⋯O hydrogen bonds, enclosing R (2) (1)(6) ring motifs, forming ribbons running along the a-axis direction. International Union of Crystallography 2014-08-30 /pmc/articles/PMC4186191/ /pubmed/25309223 http://dx.doi.org/10.1107/S1600536814018546 Text en © Kamaraj et al. 2014 http://creativecommons.org/licenses/by/2.0/uk/ This is an open-access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited.
spellingShingle Data Reports
Kamaraj, A.
Ranjith, S.
Rajkumar, R.
Mohanraj, G.
Krishnasamy, K.
Crystal structure of 1-cyclo­propane­carbon­yl-3-methyl-2,6-di-p-tolyl­piperidin-4-one
title Crystal structure of 1-cyclo­propane­carbon­yl-3-methyl-2,6-di-p-tolyl­piperidin-4-one
title_full Crystal structure of 1-cyclo­propane­carbon­yl-3-methyl-2,6-di-p-tolyl­piperidin-4-one
title_fullStr Crystal structure of 1-cyclo­propane­carbon­yl-3-methyl-2,6-di-p-tolyl­piperidin-4-one
title_full_unstemmed Crystal structure of 1-cyclo­propane­carbon­yl-3-methyl-2,6-di-p-tolyl­piperidin-4-one
title_short Crystal structure of 1-cyclo­propane­carbon­yl-3-methyl-2,6-di-p-tolyl­piperidin-4-one
title_sort crystal structure of 1-cyclo­propane­carbon­yl-3-methyl-2,6-di-p-tolyl­piperidin-4-one
topic Data Reports
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4186191/
https://www.ncbi.nlm.nih.gov/pubmed/25309223
http://dx.doi.org/10.1107/S1600536814018546
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