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Crystal structure of methyl 2-[2,4-bis(4-fluorophenyl)-3-azabicyclo[3.3.1]nonan-9-ylidene]hydrazinecarboxylate
In the title compound, C(22)H(23)F(2)N(3)O(2), the bicyclic ring system exists in a twin-chair conformation with an equatorial disposition of the 4-fluorophenyl groups on the heterocycle. These aromatic rings are inclined to one another by 19.4 (1)°. In the crystal, molecules are linked by pairs o...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
International Union of Crystallography
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4186194/ https://www.ncbi.nlm.nih.gov/pubmed/25309164 http://dx.doi.org/10.1107/S1600536814018935 |
Sumario: | In the title compound, C(22)H(23)F(2)N(3)O(2), the bicyclic ring system exists in a twin-chair conformation with an equatorial disposition of the 4-fluorophenyl groups on the heterocycle. These aromatic rings are inclined to one another by 19.4 (1)°. In the crystal, molecules are linked by pairs of N—H⋯O and C—H⋯O hydrogen bonds into inversion dimers, incorporating R (1) (2)(7) and R (2) (2)(8) ring motifs; the same O atom accepts both hydrogen bonds. These dimers are further linked by a pair of C—H⋯F hydrogen bonds, enclosing R (2) (2)(28) ring motifs, forming supramolecular chains along [010]. The NH group of the pyridine ring is not involved in hydrogen bonding, probably due to the steric hindrance of the fluorophenyl groups. |
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