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Evaluation of blood-brain barrier permeability in tryptophan hydroxylase 2-knockout mice

The blood-brain barrier (BBB) is critical to the health of the central nervous system (CNS). The possibility that 5-hydroxytryptamine (5-HT) participates in the alteration of the BBB has been previously demonstrated. Tryptophan hydroxylase 2 (TPH2) is a unique genetic enzyme isoform that catalyzes t...

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Detalles Bibliográficos
Autores principales: XU, CHAO-JIN, PENG-ZHANG, DAI, TING-LI, NIU, XUE-YUAN, WANG, JUN-LING, JIN, MING-SHUN, MIN-LIAO
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4186353/
https://www.ncbi.nlm.nih.gov/pubmed/25289042
http://dx.doi.org/10.3892/etm.2014.1938