Cargando…

Metabolomic evaluation of Mitomycin C and rapamycin in a personalized treatment of pancreatic cancer

In a personalized treatment designed for a patient with pancreatic cancer resistant to other treatments, the success of Mitomycin C (MMC) has been highlighted. This was revealed in a murine xenograft tumor model encompassing pancreatic adenocarcinoma cells extracted from the patient. The patient was...

Descripción completa

Detalles Bibliográficos
Autores principales:	Navarrete, Alicia, Armitage, Emily G, Musteanu, Monica, García, Antonia, Mastrangelo, Annalaura, Bujak, Renata, López-Casas, Pedro P, Hidalgo, Manuel, Barbas, Coral
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Blackwell Publishing Ltd 2014
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4186447/ https://www.ncbi.nlm.nih.gov/pubmed/25505613 http://dx.doi.org/10.1002/prp2.67

Ejemplares similares

Altered Metabolic and Stemness Capacity of Adipose Tissue-Derived Stem Cells from Obese Mouse and Human
por: Pérez, Laura M., et al.
Publicado: (2015)

Metabolomic-Based Methods in Diagnosis and Monitoring Infection Progression
por: Fernández-García, Miguel, et al.
Publicado: (2018)

Whole Exome Sequencing of Rapid Autopsy Tumors and Xenograft Models Reveals Possible Driver Mutations Underlying Tumor Progression
por: Xie, Tao, et al.
Publicado: (2015)

Metabolomics and neuroanatomical evaluation of post-mortem changes in the hippocampus
por: Gonzalez-Riano, Carolina, et al.
Publicado: (2017)

Metabolomic Fingerprinting in the Comprehensive Study of Liver Changes Associated with Onion Supplementation in Hypercholesterolemic Wistar Rats
por: González-Peña, Diana, et al.
Publicado: (2017)

Unveiling Metabolic Phenotype Alterations in Anorexia Nervosa through Metabolomics
por: Mayo-Martínez, Laura, et al.
Publicado: (2021)

TurboPutative: A web server for data handling and metabolite classification in untargeted metabolomics
por: Barrero-Rodríguez, Rafael, et al.
Publicado: (2022)

To treat or not to treat: metabolomics reveals biomarkers for treatment indication in chronic lymphocytic leukaemia patients
por: Piszcz, Jaroslaw, et al.
Publicado: (2016)

Rapamycin-enhanced mitomycin C-induced apoptotic death is mediated through the S6K1–Bad–Bak pathway in peritoneal carcinomatosis
por: Song, X, et al.
Publicado: (2014)

Aspergillus Metabolome Database for Mass Spectrometry Metabolomics
por: Gil-de-la-Fuente, Alberto, et al.
Publicado: (2021)

Short overview on metabolomics approach to study pathophysiology of oxidative stress in cancer
por: Andrisic, Luka, et al.
Publicado: (2017)

Olaparib in combination with irinotecan, cisplatin, and mitomycin C in patients with advanced pancreatic cancer
por: Yarchoan, Mark, et al.
Publicado: (2017)

Insulin Resistance in Obese Children: What Can Metabolomics and Adipokine Modelling Contribute?
por: Rupérez, Francisco J., et al.
Publicado: (2020)

Multiplatform Metabolomics Characterization Reveals Novel Metabolites and Phospholipid Compositional Rules of Haemophilus influenzae Rd KW20
por: Fernández-García, Miguel, et al.
Publicado: (2023)

Genomics, Transcriptomics, and Metabolomics Reveal That Minimal Modifications in the Host Are Crucial for the Compensatory Evolution of ColE1-Like Plasmids
por: Ares-Arroyo, Manuel, et al.
Publicado: (2022)

Stromal disrupting effects of nab-paclitaxel in pancreatic cancer
por: Alvarez, R, et al.
Publicado: (2013)

Metabolomics with LC-QTOF-MS Permits the Prediction of Disease Stage in Aortic Abdominal Aneurysm Based on Plasma Metabolic Fingerprint
por: Ciborowski, Michal, et al.
Publicado: (2012)

Impact of renal tubular Cpt1a overexpression on the kidney metabolome in the folic acid-induced fibrosis mouse model
por: Cuevas-Delgado, Paula, et al.
Publicado: (2023)

Transconjunctival penetration of mitomycin C
por: Velpandian, T, et al.
Publicado: (2008)

Complex Interplay between Sphingolipid and Sterol Metabolism Revealed by Perturbations to the Leishmania Metabolome Caused by Miltefosine
por: Armitage, Emily G., et al.
Publicado: (2018)

Reply: ‘Comments on Stromal disrupting effects of nab-paclitaxel in pancreatic cancer'
por: Alvarez, R, et al.
Publicado: (2014)

Molecular signature of renal cell carcinoma by means of a multiplatform metabolomics analysis
por: Kordalewska, Marta, et al.
Publicado: (2022)

Comprehensive Examination of the Mouse Lung Metabolome Following Mycobacterium tuberculosis Infection Using a Multiplatform Mass Spectrometry Approach
por: Fernández-García, Miguel, et al.
Publicado: (2020)

Insulin resistance in prepubertal obese children correlates with sex-dependent early onset metabolomic alterations
por: Mastrangelo, A, et al.
Publicado: (2016)

Mitomycin C in Homologous Recombination Deficient Metastatic Pancreatic Cancer after Disease Progression on Platinum-Based Chemotherapy and Olaparib
por: Botrus, Gehan, et al.
Publicado: (2022)

PLS-Based and Regularization-Based Methods for the Selection of Relevant Variables in Non-targeted Metabolomics Data
por: Bujak, Renata, et al.
Publicado: (2016)

Methods for direct determination of mitomycin C in aqueous solutions and in urine
por: Marín, Dolores, et al.
Publicado: (1998)

Irinotecan, cisplatin and mitomycin in inoperable gastro-oesophageal and pancreatic cancers – a new active regimen
por: Slater, S, et al.
Publicado: (2002)

Effect of photodynamic therapy in combination with mitomycin C on a mitomycin-resistant bladder cancer cell line.
por: Datta, S. N., et al.
Publicado: (1997)

Short overview on metabolomic approach and redox changes in psychiatric disorders
por: Nedic Erjavec, Gordana, et al.
Publicado: (2017)

Mitomycin C. Current Status and Developments
por: Fox, B. W.
Publicado: (1980)

EFFECTS OF MITOMYCIN C ON HUMAN CHROMOSOMES
por: Cohen, Maimon M., et al.
Publicado: (1964)

Mitomycins syntheses: a recent update
por: Andrez, Jean-Christophe
Publicado: (2009)

Effectiveness of an Immediate Mitomycin C Instillation in Patients with Superficial Bladder Cancer Receiving Periodic Mitomycin C Instillation
por: Jung, Seok Jin, et al.
Publicado: (2011)

Outcomes of Trabeculectomy With and Without Mitomycin C in Pseudoexfoliative Glaucoma Compared With Mitomycin C in Primary Open Angle Glaucoma
por: LOPES, Ana Sofia, et al.
Publicado: (2019)

Metabolomic Reprogramming of C57BL/6-Macrophages during Early Infection with L. amazonensis
por: Mamani-Huanca, Maricruz, et al.
Publicado: (2021)

Development of a Novel Targeted Metabolomic LC-QqQ-MS Method in Allergic Inflammation
por: Obeso, David, et al.
Publicado: (2022)

Plasma Metabolome Alterations Associated with Extrauterine Growth Restriction
por: Dudzik, Danuta, et al.
Publicado: (2020)

Metabolomics and biochemical alterations caused by pleiotrophin in the 6-hydroxydopamine mouse model of Parkinson’s disease
por: Gramage, Esther, et al.
Publicado: (2022)

A Multiplatform Metabolomic Approach to the Basis of Antimonial Action and Resistance in Leishmania infantum
por: Rojo, David, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_ll2q43lgl93ccsmjjiel597akd