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Smarter vaccine design will circumvent regulatory T cell-mediated evasion in chronic HIV and HCV infection
Despite years of research, vaccines against HIV and HCV are not yet available, due largely to effective viral immunoevasive mechanisms. A novel escape mechanism observed in viruses that cause chronic infection is suppression of viral-specific effector CD4(+) and CD8(+) T cells by stimulating regulat...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4186478/ https://www.ncbi.nlm.nih.gov/pubmed/25339942 http://dx.doi.org/10.3389/fmicb.2014.00502 |