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Differences in the Levels of Gastric Cancer Risk Factors Between Nanjing and Minqing Counties, China
OBJECTIVES: In Fujian Province, China, gastric cancer is one of the leading causes of mortality among all malignant tumors. Nanjing county and Minqing county are located in inland Fujian and have similar general demographics. However, the adjusted mortality rate of gastric cancer in Minqing was foun...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Korean Society for Preventive Medicine
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4186548/ https://www.ncbi.nlm.nih.gov/pubmed/25284200 http://dx.doi.org/10.3961/jpmph.14.018 |
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author | Xie, Xiang-Quan Zheng, Kui-Cheng Wu, Bing-Shan Chen, Tie-Hui Lai, Shan-Rong Lin, Zai-Sheng Aoki, Kazuo |
author_facet | Xie, Xiang-Quan Zheng, Kui-Cheng Wu, Bing-Shan Chen, Tie-Hui Lai, Shan-Rong Lin, Zai-Sheng Aoki, Kazuo |
author_sort | Xie, Xiang-Quan |
collection | PubMed |
description | OBJECTIVES: In Fujian Province, China, gastric cancer is one of the leading causes of mortality among all malignant tumors. Nanjing county and Minqing county are located in inland Fujian and have similar general demographics. However, the adjusted mortality rate of gastric cancer in Minqing was found to be much higher than that in Nanjing. We sought to explore factors associated with this increased risk of gastric cancer between the two counties. METHODS: We recruited 231 and 224 residents from Nanjing and Minqing, respectively, and analyzed differences between their dietary habits, Helicobacter pylori infection rates, and concentrations of serum pepsinogen I, pepsinogen II, gastrin-17, and ratio of pepsinogen I:II. RESULTS: Subjects in Minqing had more first-degree relatives who had been diagnosed with upper gastrointestinal tumor, more unhealthy dietary habits, a higher Helicobacter pylori positive rate, and greater proportion of abnormal serum gastrin-17 than those in Nanjing did. CONCLUSIONS: The factors that differed between these two counties might indicate that residents in Minqing have a higher risk for developing gastric cancer than those in Nanjing do. |
format | Online Article Text |
id | pubmed-4186548 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2014 |
publisher | Korean Society for Preventive Medicine |
record_format | MEDLINE/PubMed |
spelling | pubmed-41865482014-10-08 Differences in the Levels of Gastric Cancer Risk Factors Between Nanjing and Minqing Counties, China Xie, Xiang-Quan Zheng, Kui-Cheng Wu, Bing-Shan Chen, Tie-Hui Lai, Shan-Rong Lin, Zai-Sheng Aoki, Kazuo J Prev Med Public Health Original Article OBJECTIVES: In Fujian Province, China, gastric cancer is one of the leading causes of mortality among all malignant tumors. Nanjing county and Minqing county are located in inland Fujian and have similar general demographics. However, the adjusted mortality rate of gastric cancer in Minqing was found to be much higher than that in Nanjing. We sought to explore factors associated with this increased risk of gastric cancer between the two counties. METHODS: We recruited 231 and 224 residents from Nanjing and Minqing, respectively, and analyzed differences between their dietary habits, Helicobacter pylori infection rates, and concentrations of serum pepsinogen I, pepsinogen II, gastrin-17, and ratio of pepsinogen I:II. RESULTS: Subjects in Minqing had more first-degree relatives who had been diagnosed with upper gastrointestinal tumor, more unhealthy dietary habits, a higher Helicobacter pylori positive rate, and greater proportion of abnormal serum gastrin-17 than those in Nanjing did. CONCLUSIONS: The factors that differed between these two counties might indicate that residents in Minqing have a higher risk for developing gastric cancer than those in Nanjing do. Korean Society for Preventive Medicine 2014-09 2014-09-12 /pmc/articles/PMC4186548/ /pubmed/25284200 http://dx.doi.org/10.3961/jpmph.14.018 Text en Copyright © 2014 The Korean Society for Preventive Medicine This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/bync/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Original Article Xie, Xiang-Quan Zheng, Kui-Cheng Wu, Bing-Shan Chen, Tie-Hui Lai, Shan-Rong Lin, Zai-Sheng Aoki, Kazuo Differences in the Levels of Gastric Cancer Risk Factors Between Nanjing and Minqing Counties, China |
title | Differences in the Levels of Gastric Cancer Risk Factors Between Nanjing and Minqing Counties, China |
title_full | Differences in the Levels of Gastric Cancer Risk Factors Between Nanjing and Minqing Counties, China |
title_fullStr | Differences in the Levels of Gastric Cancer Risk Factors Between Nanjing and Minqing Counties, China |
title_full_unstemmed | Differences in the Levels of Gastric Cancer Risk Factors Between Nanjing and Minqing Counties, China |
title_short | Differences in the Levels of Gastric Cancer Risk Factors Between Nanjing and Minqing Counties, China |
title_sort | differences in the levels of gastric cancer risk factors between nanjing and minqing counties, china |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4186548/ https://www.ncbi.nlm.nih.gov/pubmed/25284200 http://dx.doi.org/10.3961/jpmph.14.018 |
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