Cargando…

Differences in the Levels of Gastric Cancer Risk Factors Between Nanjing and Minqing Counties, China

OBJECTIVES: In Fujian Province, China, gastric cancer is one of the leading causes of mortality among all malignant tumors. Nanjing county and Minqing county are located in inland Fujian and have similar general demographics. However, the adjusted mortality rate of gastric cancer in Minqing was foun...

Descripción completa

Detalles Bibliográficos
Autores principales: Xie, Xiang-Quan, Zheng, Kui-Cheng, Wu, Bing-Shan, Chen, Tie-Hui, Lai, Shan-Rong, Lin, Zai-Sheng, Aoki, Kazuo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society for Preventive Medicine 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4186548/
https://www.ncbi.nlm.nih.gov/pubmed/25284200
http://dx.doi.org/10.3961/jpmph.14.018
_version_ 1782338077551755264
author Xie, Xiang-Quan
Zheng, Kui-Cheng
Wu, Bing-Shan
Chen, Tie-Hui
Lai, Shan-Rong
Lin, Zai-Sheng
Aoki, Kazuo
author_facet Xie, Xiang-Quan
Zheng, Kui-Cheng
Wu, Bing-Shan
Chen, Tie-Hui
Lai, Shan-Rong
Lin, Zai-Sheng
Aoki, Kazuo
author_sort Xie, Xiang-Quan
collection PubMed
description OBJECTIVES: In Fujian Province, China, gastric cancer is one of the leading causes of mortality among all malignant tumors. Nanjing county and Minqing county are located in inland Fujian and have similar general demographics. However, the adjusted mortality rate of gastric cancer in Minqing was found to be much higher than that in Nanjing. We sought to explore factors associated with this increased risk of gastric cancer between the two counties. METHODS: We recruited 231 and 224 residents from Nanjing and Minqing, respectively, and analyzed differences between their dietary habits, Helicobacter pylori infection rates, and concentrations of serum pepsinogen I, pepsinogen II, gastrin-17, and ratio of pepsinogen I:II. RESULTS: Subjects in Minqing had more first-degree relatives who had been diagnosed with upper gastrointestinal tumor, more unhealthy dietary habits, a higher Helicobacter pylori positive rate, and greater proportion of abnormal serum gastrin-17 than those in Nanjing did. CONCLUSIONS: The factors that differed between these two counties might indicate that residents in Minqing have a higher risk for developing gastric cancer than those in Nanjing do.
format Online
Article
Text
id pubmed-4186548
institution National Center for Biotechnology Information
language English
publishDate 2014
publisher Korean Society for Preventive Medicine
record_format MEDLINE/PubMed
spelling pubmed-41865482014-10-08 Differences in the Levels of Gastric Cancer Risk Factors Between Nanjing and Minqing Counties, China Xie, Xiang-Quan Zheng, Kui-Cheng Wu, Bing-Shan Chen, Tie-Hui Lai, Shan-Rong Lin, Zai-Sheng Aoki, Kazuo J Prev Med Public Health Original Article OBJECTIVES: In Fujian Province, China, gastric cancer is one of the leading causes of mortality among all malignant tumors. Nanjing county and Minqing county are located in inland Fujian and have similar general demographics. However, the adjusted mortality rate of gastric cancer in Minqing was found to be much higher than that in Nanjing. We sought to explore factors associated with this increased risk of gastric cancer between the two counties. METHODS: We recruited 231 and 224 residents from Nanjing and Minqing, respectively, and analyzed differences between their dietary habits, Helicobacter pylori infection rates, and concentrations of serum pepsinogen I, pepsinogen II, gastrin-17, and ratio of pepsinogen I:II. RESULTS: Subjects in Minqing had more first-degree relatives who had been diagnosed with upper gastrointestinal tumor, more unhealthy dietary habits, a higher Helicobacter pylori positive rate, and greater proportion of abnormal serum gastrin-17 than those in Nanjing did. CONCLUSIONS: The factors that differed between these two counties might indicate that residents in Minqing have a higher risk for developing gastric cancer than those in Nanjing do. Korean Society for Preventive Medicine 2014-09 2014-09-12 /pmc/articles/PMC4186548/ /pubmed/25284200 http://dx.doi.org/10.3961/jpmph.14.018 Text en Copyright © 2014 The Korean Society for Preventive Medicine This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/bync/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Article
Xie, Xiang-Quan
Zheng, Kui-Cheng
Wu, Bing-Shan
Chen, Tie-Hui
Lai, Shan-Rong
Lin, Zai-Sheng
Aoki, Kazuo
Differences in the Levels of Gastric Cancer Risk Factors Between Nanjing and Minqing Counties, China
title Differences in the Levels of Gastric Cancer Risk Factors Between Nanjing and Minqing Counties, China
title_full Differences in the Levels of Gastric Cancer Risk Factors Between Nanjing and Minqing Counties, China
title_fullStr Differences in the Levels of Gastric Cancer Risk Factors Between Nanjing and Minqing Counties, China
title_full_unstemmed Differences in the Levels of Gastric Cancer Risk Factors Between Nanjing and Minqing Counties, China
title_short Differences in the Levels of Gastric Cancer Risk Factors Between Nanjing and Minqing Counties, China
title_sort differences in the levels of gastric cancer risk factors between nanjing and minqing counties, china
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4186548/
https://www.ncbi.nlm.nih.gov/pubmed/25284200
http://dx.doi.org/10.3961/jpmph.14.018
work_keys_str_mv AT xiexiangquan differencesinthelevelsofgastriccancerriskfactorsbetweennanjingandminqingcountieschina
AT zhengkuicheng differencesinthelevelsofgastriccancerriskfactorsbetweennanjingandminqingcountieschina
AT wubingshan differencesinthelevelsofgastriccancerriskfactorsbetweennanjingandminqingcountieschina
AT chentiehui differencesinthelevelsofgastriccancerriskfactorsbetweennanjingandminqingcountieschina
AT laishanrong differencesinthelevelsofgastriccancerriskfactorsbetweennanjingandminqingcountieschina
AT linzaisheng differencesinthelevelsofgastriccancerriskfactorsbetweennanjingandminqingcountieschina
AT aokikazuo differencesinthelevelsofgastriccancerriskfactorsbetweennanjingandminqingcountieschina