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Regulation of insulin-like growth factor signaling by metformin in endometrial cancer cells

Obesity, diabetes and insulin resistance are marked risk factors that promote the development of type I endometrial cancer. Previous studies have demonstrated that insulin-like growth factor 1 (IGF-1) and IGF-2 promote cell proliferation in endometrial cancer cells, while metformin reverses this eff...

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Detalles Bibliográficos
Autores principales:	XIE, YA, WANG, JING-LU, JI, MEI, YUAN, ZHONG-FU, PENG, ZHENG, ZHANG, YI, WEN, JIAN-GUO, SHI, HUI-RONG
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2014
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4186557/ https://www.ncbi.nlm.nih.gov/pubmed/25289085 http://dx.doi.org/10.3892/ol.2014.2466

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