Cargando…

Decitabine inhibits the cell growth of cholangiocarcinoma in cultured cell lines and mouse xenografts

Decitabine (DAC), an inhibitor of DNA methyltransferase, demonstrates antitumor activities in various types of cancer. However, its therapeutic potential for cholangiocarcinoma (CCA), one of the most aggressive gastrointestinal malignancies, remains to be explored. The present study investigated the...

Descripción completa

Detalles Bibliográficos
Autores principales:	WANG, BING, LI, HONGBO, YANG, RUI, ZHOU, SHUNCHANG, ZOU, SHENGQUAN
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2014
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4186605/ https://www.ncbi.nlm.nih.gov/pubmed/25295073 http://dx.doi.org/10.3892/ol.2014.2499

Ejemplares similares

Sodium Valproate Inhibits the Growth of Human Cholangiocarcinoma In Vitro and In Vivo
por: Wang, Bing, et al.
Publicado: (2013)

Establishment of Highly Transplantable Cholangiocarcinoma Cell Lines from a Patient-Derived Xenograft Mouse Model
por: Vaeteewoottacharn, Kulthida, et al.
Publicado: (2019)

Therapeutic effect of TRC105 and decitabine combination in AML xenografts
por: Baik, June, et al.
Publicado: (2020)

Antitumor Effects of Delta (9)-Tetrahydrocannabinol and Cannabinol on Cholangiocarcinoma Cells and Xenograft Mouse Models
por: Leelawat, Surang, et al.
Publicado: (2022)

Tiliacora triandra Leaf Powder Ethanolic Extract in Combination with Cisplatin or Gemcitabine Synergistically Inhibits the Growth of Cholangiocarcinoma Cells In Vitro and in Nude Mouse Xenograft Models
por: Samankul, Arunta, et al.
Publicado: (2023)

Modulation by decitabine of gene expression and growth of osteosarcoma U2OS cells in vitro and in xenografts: Identification of apoptotic genes as targets for demethylation
por: Al-Romaih, Khaldoun, et al.
Publicado: (2007)

MicroRNA-144 suppresses cholangiocarcinoma cell proliferation and invasion through targeting platelet activating factor acetylhydrolase isoform 1b
por: Yang, Rui, et al.
Publicado: (2014)

The combination of decitabine and aspirin inhibits tumor growth and metastasis in non-small cell lung cancer
por: Xu, Maoyi, et al.
Publicado: (2022)

A Comparison of Azacitidine and Decitabine Activities in Acute Myeloid Leukemia Cell Lines
por: Hollenbach, Paul W., et al.
Publicado: (2010)

Inhibition of growth and migration of cholangiocarcinoma cells by pamidronate
por: Buranrat, Benjaporn, et al.
Publicado: (2019)

Efficient induction of differentiation and growth inhibition in IDH1 mutant glioma cells by the DNMT Inhibitor Decitabine
por: Turcan, Sevin, et al.
Publicado: (2013)

Decitabine inhibits T cell proliferation via a novel TET2-dependent mechanism and exerts potent protective effect in mouse auto- and allo-immunity models
por: Wang, Xue, et al.
Publicado: (2017)

Inhibition of proteasome activity by the dietary flavonoid apigenin is associated with growth inhibition in cultured breast cancer cells and xenografts
por: Chen, Di, et al.
Publicado: (2007)

Eribulin inhibits growth of cutaneous squamous cell carcinoma cell lines and a novel patient-derived xenograft
por: Hsu, Che-Yuan, et al.
Publicado: (2023)

Metformin inhibits growth and prolactin secretion of pituitary prolactinoma cells and xenografts
por: Gao, Jun, et al.
Publicado: (2018)

Quantitative proteomic analysis of histone modifications in decitabine sensitive and resistant leukemia cell lines
por: Zhang, Chunchao, et al.
Publicado: (2016)

Comprehensive comparison between azacytidine and decitabine treatment in an acute myeloid leukemia cell line
por: Aumer, Tina, et al.
Publicado: (2022)

Gliotoxin Targets Nuclear NOTCH2 in Human Solid Tumor Derived Cell Lines In Vitro and Inhibits Melanoma Growth in Xenograft Mouse Model
por: Hubmann, Rainer, et al.
Publicado: (2017)

Expression of growth factor receptors and targeting of EGFR in cholangiocarcinoma cell lines
por: Xu, Ling, et al.
Publicado: (2010)

Inhibition of PI3K by copanlisib exerts potent antitumor effects on Merkel cell carcinoma cell lines and mouse xenografts
por: Fang, Bin, et al.
Publicado: (2020)

Inhibition of Human Pancreatic Tumor Growth by Cytokine-Induced Killer Cells in Nude Mouse Xenograft Model
por: Kim, Ji Sung, et al.
Publicado: (2012)

Gene and microRNA modulation upon trabectedin treatment in a human intrahepatic cholangiocarcinoma paired patient derived xenograft and cell line
por: Peraldo Neia, Caterina, et al.
Publicado: (2016)

Histone deacetylase 3 overexpression in human cholangiocarcinoma and promotion of cell growth via apoptosis inhibition
por: Yin, Yuyao, et al.
Publicado: (2017)

Galangin Inhibits Cholangiocarcinoma Cell Growth and Metastasis through Downregulation of MicroRNA-21 Expression
por: Zou, Yang, et al.
Publicado: (2020)

Venetoclax with decitabine or azacitidine in the first‐line treatment of acute myeloid leukemia
por: Bouligny, Ian M., et al.
Publicado: (2023)

Down-regulation of HDAC3 inhibits growth of cholangiocarcinoma by inducing apoptosis
por: Zhang, Mingming, et al.
Publicado: (2017)

QUANTITATIVE STUDIES OF THE GROWTH OF MOUSE EMBRYO CELLS IN CULTURE AND THEIR DEVELOPMENT INTO ESTABLISHED LINES
por: Todaro, George J., et al.
Publicado: (1963)

Azacytidine and Decitabine Induce Gene-Specific and Non-Random DNA Demethylation in Human Cancer Cell Lines
por: Hagemann, Sabine, et al.
Publicado: (2011)

Synergistic inhibitory effects of low-dose decitabine in combination with bortezomib in the AML cell line Kasumi-1
por: Mpakou, Vassiliki, et al.
Publicado: (2021)

Di-O-lauroyl-decitabine-lipid nanocapsules: toward extending decitabine activity
por: Briot, Thomas, et al.
Publicado: (2019)

Genetic and phenotypic determinants of morphologies in 3D cultures and xenografts of lung tumor cell lines
por: Matsubara, Daisuke, et al.
Publicado: (2023)

Decitabine Inhibits Gamma Delta T Cell Cytotoxicity by Promoting KIR2DL2/3 Expression
por: Niu, Chao, et al.
Publicado: (2018)

Establishment and molecular characterization of decitabine‐resistant K562 cells
por: Wen, Xiang‐Mei, et al.
Publicado: (2019)

Comparison of growth features and cancer stem cell prevalence in intrahepatic and extrahepatic cholangiocarcinoma cell lines
por: Yang, Jiaqi, et al.
Publicado: (2022)

Establishment and Characterization of Two Novel Cholangiocarcinoma Cell Lines
por: Zhang, Yanhua, et al.
Publicado: (2019)

Effect of the GLP-1 Analog Exendin-4 and Oxaliplatin on Intrahepatic Cholangiocarcinoma Cell Line and Mouse Model
por: Chen, Ben-Dong, et al.
Publicado: (2013)

A Novel Cell Line Based Orthotopic Xenograft Mouse Model That Recapitulates Human Hepatoblastoma
por: Woodfield, Sarah E., et al.
Publicado: (2017)

Proscillaridin A is cytotoxic for glioblastoma cell lines and controls tumor xenograft growth in vivo
por: Denicolaï, Emilie, et al.
Publicado: (2014)

Let-7c inhibits cholangiocarcinoma growth but promotes tumor cell invasion and growth at extrahepatic sites
por: Xie, Yu, et al.
Publicado: (2018)

Shikonin Inhibits Cholangiocarcinoma Cell Line QBC939 by Regulating Apoptosis, Proliferation, and Invasion
por: Liu, Chang, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_khoaqffn7i51utg1l7ov16h871