Synthesis, Characterization, and X-ray Attenuation Properties of Ultrasmall BiOI Nanoparticles: Toward Renal Clearable Particulate CT Contrast Agents

[Image: see text] A unique decelerated hydrolytic procedure is developed and reported here for the preparation of ultrasmall nanoparticles (NPs) of PVP-coated BiOI with a narrow size distribution, i.e., 2.8 ± 0.5 nm. The crystal structure of this compound is determined by X-ray powder diffraction us...

Descripción completa

Detalles Bibliográficos
Autores principales: Kandanapitiye, Murthi S., Gao, Min, Molter, Joseph, Flask, Chris A., Huang, Songping D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4186669/
https://www.ncbi.nlm.nih.gov/pubmed/25283335
http://dx.doi.org/10.1021/ic5011709
_version_ 1782338099342213120
author Kandanapitiye, Murthi S.
Gao, Min
Molter, Joseph
Flask, Chris A.
Huang, Songping D.
author_facet Kandanapitiye, Murthi S.
Gao, Min
Molter, Joseph
Flask, Chris A.
Huang, Songping D.
author_sort Kandanapitiye, Murthi S.
collection PubMed
description [Image: see text] A unique decelerated hydrolytic procedure is developed and reported here for the preparation of ultrasmall nanoparticles (NPs) of PVP-coated BiOI with a narrow size distribution, i.e., 2.8 ± 0.5 nm. The crystal structure of this compound is determined by X-ray powder diffraction using the bulk materials. The stability, cytotoxicity, and potential use of the PVP-coated ultrasmall BiOI NPs as a CT contrast agent are investigated. Because of the combined X-ray attenuation effect of bismuth and iodine, such NPs exhibit a CT value that is among the best of those of the inorganic nanoparticle-based CT contrast agents reported in the literature.
format Online
Article
Text
id pubmed-4186669
institution National Center for Biotechnology Information
language English
publishDate 2014
publisher American Chemical Society
record_format MEDLINE/PubMed
spelling pubmed-41866692015-09-09 Synthesis, Characterization, and X-ray Attenuation Properties of Ultrasmall BiOI Nanoparticles: Toward Renal Clearable Particulate CT Contrast Agents Kandanapitiye, Murthi S. Gao, Min Molter, Joseph Flask, Chris A. Huang, Songping D. Inorg Chem [Image: see text] A unique decelerated hydrolytic procedure is developed and reported here for the preparation of ultrasmall nanoparticles (NPs) of PVP-coated BiOI with a narrow size distribution, i.e., 2.8 ± 0.5 nm. The crystal structure of this compound is determined by X-ray powder diffraction using the bulk materials. The stability, cytotoxicity, and potential use of the PVP-coated ultrasmall BiOI NPs as a CT contrast agent are investigated. Because of the combined X-ray attenuation effect of bismuth and iodine, such NPs exhibit a CT value that is among the best of those of the inorganic nanoparticle-based CT contrast agents reported in the literature. American Chemical Society 2014-09-09 2014-10-06 /pmc/articles/PMC4186669/ /pubmed/25283335 http://dx.doi.org/10.1021/ic5011709 Text en Copyright © 2014 American Chemical Society Terms of Use (http://pubs.acs.org/page/policy/authorchoice_termsofuse.html)
spellingShingle Kandanapitiye, Murthi S.
Gao, Min
Molter, Joseph
Flask, Chris A.
Huang, Songping D.
Synthesis, Characterization, and X-ray Attenuation Properties of Ultrasmall BiOI Nanoparticles: Toward Renal Clearable Particulate CT Contrast Agents
title Synthesis, Characterization, and X-ray Attenuation Properties of Ultrasmall BiOI Nanoparticles: Toward Renal Clearable Particulate CT Contrast Agents
title_full Synthesis, Characterization, and X-ray Attenuation Properties of Ultrasmall BiOI Nanoparticles: Toward Renal Clearable Particulate CT Contrast Agents
title_fullStr Synthesis, Characterization, and X-ray Attenuation Properties of Ultrasmall BiOI Nanoparticles: Toward Renal Clearable Particulate CT Contrast Agents
title_full_unstemmed Synthesis, Characterization, and X-ray Attenuation Properties of Ultrasmall BiOI Nanoparticles: Toward Renal Clearable Particulate CT Contrast Agents
title_short Synthesis, Characterization, and X-ray Attenuation Properties of Ultrasmall BiOI Nanoparticles: Toward Renal Clearable Particulate CT Contrast Agents
title_sort synthesis, characterization, and x-ray attenuation properties of ultrasmall bioi nanoparticles: toward renal clearable particulate ct contrast agents
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4186669/
https://www.ncbi.nlm.nih.gov/pubmed/25283335
http://dx.doi.org/10.1021/ic5011709
work_keys_str_mv AT kandanapitiyemurthis synthesischaracterizationandxrayattenuationpropertiesofultrasmallbioinanoparticlestowardrenalclearableparticulatectcontrastagents
AT gaomin synthesischaracterizationandxrayattenuationpropertiesofultrasmallbioinanoparticlestowardrenalclearableparticulatectcontrastagents
AT molterjoseph synthesischaracterizationandxrayattenuationpropertiesofultrasmallbioinanoparticlestowardrenalclearableparticulatectcontrastagents
AT flaskchrisa synthesischaracterizationandxrayattenuationpropertiesofultrasmallbioinanoparticlestowardrenalclearableparticulatectcontrastagents
AT huangsongpingd synthesischaracterizationandxrayattenuationpropertiesofultrasmallbioinanoparticlestowardrenalclearableparticulatectcontrastagents

Ejemplares similares