Cargando…

Adjuvant Cationic Liposomes Presenting MPL and IL-12 Induce Cell Death, Suppress Tumor Growth, and Alter the Cellular Phenotype of Tumors in a Murine Model of Breast Cancer

[Image: see text] Dendritic cells (DC) process and present antigens to T lymphocytes, inducing potent immune responses when encountered in association with activating signals, such as pathogen-associated molecular patterns. Using the 4T1 murine model of breast cancer, cationic liposomes containing m...

Descripción completa

Detalles Bibliográficos
Autores principales:	Meraz, Ismail M., Savage, David J., Segura-Ibarra, Victor, Li, Jeffrey, Rhudy, Jessica, Gu, Jianhua, Serda, Rita E.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2014
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4186679/ https://www.ncbi.nlm.nih.gov/pubmed/25179345 http://dx.doi.org/10.1021/mp5002697

Ejemplares similares

Multivalent Presentation of MPL by Porous Silicon Microparticles Favors T Helper 1 Polarization Enhancing the Anti-Tumor Efficacy of Doxorubicin Nanoliposomes
por: Meraz, Ismail M., et al.
Publicado: (2014)

Comparison of BCG, MPL and cationic liposome adjuvant systems in leishmanial antigen vaccine formulations against murine visceral leishmaniasis
por: Ravindran, Rajesh, et al.
Publicado: (2010)

Potentiating Effects of MPL on DSPC Bearing Cationic Liposomes Promote Recombinant GP63 Vaccine Efficacy: High Immunogenicity and Protection
por: Mazumder, Saumyabrata, et al.
Publicado: (2011)

Combining Cationic Liposomal Delivery with MPL-TDM for Cysteine Protease Cocktail Vaccination against Leishmania donovani : Evidence for Antigen Synergy and Protection
por: Das, Amrita, et al.
Publicado: (2014)

MPL Adjuvant Contains Competitive Antagonists of Human TLR4
por: Wang, Yi-Qi, et al.
Publicado: (2020)

Correction: Combining Cationic Liposomal Delivery with MPL-TDM for Cysteine Protease Cocktail Vaccination against Leishmania donovani: Evidence for Antigen Synergy and Protection
por: Das, Amrita, et al.
Publicado: (2015)

The physiology of cardiovascular disease and innovative liposomal platforms for therapy
por: Ruiz-Esparza, Guillermo U, et al.
Publicado: (2013)

Expression pattern of the thrombopoietin receptor (Mpl) in the murine central nervous system
por: Ivanova, Anna, et al.
Publicado: (2010)

Small Cationic DDA:TDB Liposomes as Protein Vaccine Adjuvants Obviate the Need for TLR Agonists in Inducing Cellular and Humoral Responses
por: Milicic, Anita, et al.
Publicado: (2012)

Preparation, characterization, and efficient transfection of cationic liposomes and nanomagnetic cationic liposomes
por: Samadikhah, Hamid Reza, et al.
Publicado: (2011)

c-Mpl-del, a c-Mpl alternative splicing isoform, promotes AMKL progression and chemoresistance
por: Li, Fei, et al.
Publicado: (2022)

Applying Microfluidics for the Production of the Cationic Liposome-Based Vaccine Adjuvant CAF09b
por: Schmidt, Signe Tandrup, et al.
Publicado: (2020)

Enhanced localization of anticancer drug in tumor tissue using polyethylenimine-conjugated cationic liposomes
por: Han, Hee Dong, et al.
Publicado: (2014)

Immunogenicity and protection effects of cationic liposome containing imiquimod adjuvant on leishmaniasis in BALB/c mice
por: Mehravaran, Ahmad, et al.
Publicado: (2019)

TPO/Mpl Studies in Agnogenic Myeloid Metaplasia
por: Hemavathy, Kirugaval C, et al.
Publicado: (2005)

The Main (Glyco) Phospholipid (MPL) of Thermoplasma acidophilum
por: Freisleben, Hans-Joachim
Publicado: (2019)

Effect of Cationic Lipid Type in Folate-PEG-Modified Cationic Liposomes on Folate Receptor-Mediated siRNA Transfection in Tumor Cells
por: Hattori, Yoshiyuki, et al.
Publicado: (2019)

Hybrid liposomes inhibit tumor growth and lung metastasis of murine osteosarcoma cells
por: Kitajima, Hideki, et al.
Publicado: (2013)

Vaccination of mice with hybrid protein containing Exotoxin S and PcrV with adjuvants alum and MPL protects Pseudomonas aeruginosa infections
por: Asadi Karam, Mohammad Reza, et al.
Publicado: (2022)

CAMT-MPL: congenital amegakaryocytic thrombocytopenia caused by MPL mutations - heterogeneity of a monogenic disorder - a comprehensive analysis of 56 patients
por: Germeshausen, Manuela, et al.
Publicado: (2020)

Prevention of liver tumor formation in woodchucks with established hepatocellular carcinoma by treatment with cationic liposome-DNA complexes
por: Fairman, Jeffery, et al.
Publicado: (2017)

Comparison of the cellular transport mechanism of cationic, star-shaped polymers and liposomes in HaCat cells
por: Luo, Heng-Cong, et al.
Publicado: (2017)

Interactions of a Water-Soluble Glycofullerene with Glucose Transporter 1. Analysis of the Cellular Effects on a Pancreatic Tumor Model
por: Barańska, Edyta, et al.
Publicado: (2021)

Adjuvant Effect of Cationic Liposomes for Subunit Influenza Vaccine: Influence of Antigen Loading Method, Cholesterol and Immune Modulators
por: Barnier-Quer, Christophe, et al.
Publicado: (2013)

Nonfamilial, MPL S505N-Mutated Essential Thrombocythaemia
por: Morrell, Ruth, et al.
Publicado: (2013)

MPL-mutated essential thrombocythemia: a morphologic reappraisal
por: Szuber, Natasha, et al.
Publicado: (2018)

Folate-Equipped Cationic Liposomes Deliver Anti-MDR1-siRNA to the Tumor and Increase the Efficiency of Chemotherapy
por: Gladkikh, Daniil V., et al.
Publicado: (2021)

Cationic Liposomes Formulated with Synthetic Mycobacterial Cordfactor (CAF01): A Versatile Adjuvant for Vaccines with Different Immunological Requirements
por: Agger, Else Marie, et al.
Publicado: (2008)

Intradermal Immunization of SARS-CoV-2 Original Strain Trimeric Spike Protein Associated to CpG and AddaS03 Adjuvants, but Not MPL, Provide Strong Humoral and Cellular Response in Mice
por: Firmino-Cruz, Luan, et al.
Publicado: (2022)

Preparation and Characterization of New Liposomes. Bactericidal Activity of Cefepime Encapsulated into Cationic Liposomes
por: Moyá, Maria Luisa, et al.
Publicado: (2019)

Dissection of Signaling Events Downstream of the c-Mpl Receptor in Murine Hematopoietic Stem Cells Via Motif-Engineered Chimeric Receptors
por: Saka, Koichiro, et al.
Publicado: (2017)

Redirecting adenovirus to pulmonary endothelium by cationic liposomes
por: Ma, Z, et al.
Publicado: (2002)

Lnk Inhibits Tpo–mpl Signaling and Tpo-mediated Megakaryocytopoiesis
por: Tong, Wei, et al.
Publicado: (2004)

Serum Thrombopoietin and cMpl Expression in Thrombocytopenia of Different Etiologies
por: Vianello, Fabrizio, et al.
Publicado: (2014)

Expression of CALR mutants causes mpl-dependent thrombocytosis in zebrafish
por: Lim, K-H, et al.
Publicado: (2016)

Two activating mutations of MPL in triple‐negative myeloproliferative neoplasms
por: Xie, Juan, et al.
Publicado: (2019)

Identification of MPL R102P Mutation in Hereditary Thrombocytosis
por: Bellanné-Chantelot, Christine, et al.
Publicado: (2017)

The Thrombopoietin Receptor, MPL, Is a Therapeutic Target of Opportunity in the MPN
por: Spivak, Jerry L., et al.
Publicado: (2021)

Expanding the SiMPl Plasmid Toolbox for Use with Spectinomycin/Streptomycin
por: Palanisamy, Navaneethan, et al.
Publicado: (2021)

Characterization of Free and Porous Silicon-Encapsulated Superparamagnetic Iron Oxide Nanoparticles as Platforms for the Development of Theranostic Vaccines
por: Lundquist, Charles M., et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_bndohjkjr6nb2fbln18ajb747q