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Mad2 Checkpoint Gene Silencing Using Epidermal Growth Factor Receptor-Targeted Chitosan Nanoparticles in Non-Small Cell Lung Cancer Model

[Image: see text] RNA interference has emerged as a powerful strategy in cancer therapy because it allows silencing of specific genes associated with tumor progression and resistance. Mad2 is an essential mitotic checkpoint component required for accurate chromosome segregation during mitosis, and i...

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Detalles Bibliográficos
Autores principales: Nascimento, Ana Vanessa, Singh, Amit, Bousbaa, Hassan, Ferreira, Domingos, Sarmento, Bruno, Amiji, Mansoor M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4186685/
https://www.ncbi.nlm.nih.gov/pubmed/25256346
http://dx.doi.org/10.1021/mp5002894