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Structural and Energetic Effects of A(2A) Adenosine Receptor Mutations on Agonist and Antagonist Binding
To predict structural and energetic effects of point mutations on ligand binding is of considerable interest in biochemistry and pharmacology. This is not only useful in connection with site-directed mutagenesis experiments, but could also allow interpretation and prediction of individual responses...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2014
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4186821/ https://www.ncbi.nlm.nih.gov/pubmed/25285959 http://dx.doi.org/10.1371/journal.pone.0108492 |