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The Apolipoprotein-AI Mimetic Peptide L4F at a Modest Dose Does Not Attenuate Weight Gain, Inflammation, or Atherosclerosis in LDLR-Null Mice
OBJECTIVE: High density lipoprotein (HDL) cholesterol levels are inversely related to cardiovascular disease risk and associated with a reduced risk of type 2 diabetes. Apolipoprotein A-I (apoA-I; major HDL protein) mimetics have been reported to reduce atherosclerosis and decrease adiposity. This s...
Autores principales: | Averill, Michelle M., Kim, Eung Ju, Goodspeed, Leela, Wang, Shari, Subramanian, Savitha, Den Hartigh, Laura J., Tang, Chongren, Ding, Yilei, Reardon, Catherine A., Getz, Godfrey S., Chait, Alan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4186861/ https://www.ncbi.nlm.nih.gov/pubmed/25286043 http://dx.doi.org/10.1371/journal.pone.0109252 |
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