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Combined Treatment of Xenon and Hypothermia in Newborn Rats - Additive or Synergistic Effect?

BACKGROUND: Breathing the inert gas Xenon (Xe) enhances hypothermic (HT) neuroprotection after hypoxia-ischemia (HI) in small and large newborn animal models. The underlying mechanism of the enhancement is not yet fully understood, but the combined effect of Xe and HT could either be synergistic (la...

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Detalles Bibliográficos
Autores principales: Sabir, Hemmen, Walløe, Lars, Dingley, John, Smit, Elisa, Liu, Xun, Thoresen, Marianne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4186877/
https://www.ncbi.nlm.nih.gov/pubmed/25286345
http://dx.doi.org/10.1371/journal.pone.0109845