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Effects of Single Injection of Local Anesthetic Agents on Intervertebral Disc Degeneration: Ex Vivo and Long-Term In Vivo Experimental Study

BACKGROUND: Analgesic discography (discoblock) can be used to diagnose or treat discogenic low back pain by injecting a small amount of local anesthetics. However, recent in vitro studies have revealed cytotoxic effects of local anesthetics on intervertebral disc (IVD) cells. Here we aimed to invest...

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Detalles Bibliográficos
Autores principales:	Iwasaki, Koji, Sudo, Hideki, Yamada, Katsuhisa, Higashi, Hideaki, Ohnishi, Takashi, Tsujimoto, Takeru, Iwasaki, Norimasa
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4186881/ https://www.ncbi.nlm.nih.gov/pubmed/25286407 http://dx.doi.org/10.1371/journal.pone.0109851

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